[The interrelations of the human and avian influenza viruses A(H2) determined by the mathematical processing of data on the antigenic structure of their hemagglutinin].

Abstract

Mathematical methods were used to analyse the data on the antigenic specificity of H2 subtype hemagglutinin of human and avian influenza A viruses. This approach allowed the evaluation of possible evolutional relationships in this little-studied group of viruses. Influenza A (H2) viruses isolated from birds in the USA were found to represent a sufficiently isolated group, whereas European avian strains (A/duck/Germany/1215/73, A/pintail duck/Primor'e/695/76, A/duck/Marseilles/46/76) were close to "human" viruses. The A/Leningrad/1468/65, A/laughing gull/New Jersey/75/85, and A/pintail duck/Alberta/2728/77 strains represent marked antigenic variants apparently rather far gone as a result of hemagglutinin drift.

• Authors: E A Govorkova, V M Kibardin, A A Kizina, G M Nazarova, Iu A Smirnov
• Journal: Voprosy virusologii (Vopr Virusol) 1991 Nov-Dec Vol. 36 Issue 6 Pg. 463-7 ISSN: 0507-4088 [Print] Russia (Federation)
• Vernacular Title: Vzaimosviazi virusov grippa A(H2) cheloveka i ptits, opredeliaemye matematicheskoĭ obrabotkoĭ dannykh ob antigennoĭ strukture gemagglutinina.
• PMID: 1785179 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Antigens, Viral
• Hemagglutinins, Viral

Topics

• Algorithms
• Animals
• Antigenic Variation (immunology)
• Antigens, Viral (classification, immunology)
• Biological Evolution
• Cluster Analysis
• Ducks (microbiology)
• Hemagglutinins, Viral (classification, immunology)
• Humans
• Influenza A virus (classification, immunology)