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HLA antigen frequencies in children with cardiac disease in Cairo.

Abstract
The study of Histocompatibility Locus Antigen (HLA) frequencies in 48 cases with congenital heart disease (CHD) in children in Cairo showed high incidence of A10. Cases with atrial septal defect have shown a significant association with A3 besides A10. There is also a significant association between B12-45 and right loop anomalies (Fallot's and pulmonary stenosis) together with A10. On the other hand, children with rheumatic heart disease have shown strong positive association with HLA group B8 and negative association with A28.
AuthorsA M Eissa, S el-Tayeb, N M Nour
JournalJournal of tropical pediatrics (J Trop Pediatr) Vol. 37 Issue 5 Pg. 226-31 (10 1991) ISSN: 0142-6338 [Print] England
PMID1784055 (Publication Type: Journal Article)
Chemical References
  • HLA Antigens
Topics
  • Adolescent
  • Child
  • Egypt
  • Female
  • HLA Antigens (blood)
  • Heart Defects, Congenital (immunology)
  • Humans
  • Male
  • Risk Factors

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