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Photodynamic therapy for the treatment of actinic cheilitis.

AbstractAlthough actinic cheilitis is a common disease, it should be treated carefully because it can undergo malignant transformation. We report a case of actinic cheilitis treated with photodynamic therapy (PDT) using 5-aminolevulinic acid (ALA), with satisfactory outcome in both clinical and pathological aspects. Actinic cheilitis is a pathologic condition affecting mainly the lower lip caused by long-term exposure of the lips to the UV radiation in sunlight. Analogous to actinic keratosis of the skin, actinic cheilitis is considered as a precancerous lesion and it may develop into squamous cell carcinoma. We report a case of actinic cheilitis treated with PDT using ALA, with satisfactory outcome in both clinical and pathological aspects.
AuthorsMakiko Kodama, Daisuke Watanabe, Yoichi Akita, Yasuhiko Tamada, Yoshinari Matsumoto (Affiliation: Department of Dermatology, Aichi Medical University, Aichi, Japan.)
JournalPhotodermatology, photoimmunology & photomedicine (Photodermatol Photoimmunol Photomed) Vol. 23 Issue 5 Pg. 209-10 (Oct 2007) ISSN: 0905-4383 Denmark
PMID17803601 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Aminolevulinic Acid
Topics
  • Aged
  • Aminolevulinic Acid (therapeutic use)
  • Cheilitis (drug therapy, etiology)
  • Female
  • Humans
  • Photochemotherapy
  • Sunlight (adverse effects)