[Treatment of immunodeficient conditions caused by viral infection with the Soviet immunomodulator kemantan in patients with pulmonary tuberculosis].
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| Abstract |
Observation of 219 patients with pulmonary tuberculosis was made to study the effect of acute respiratory viral infection (ARVI) on the course of the disease. The affected were divided into 2 groups: 136 subjects who had ARVI and 83 persons who did not have it during their stay at a hospital. Patients with infiltrative pulmonary tuberculosis, and young and middle-aged men were prevalent in both groups. It was found that ARVI promoted the aggravation of a specific process in the lungs in 19.1 per cent of the patients. Keeping in mind a large proportion of aggravations and low immunologic indices as a consequence of ARVI, 14 patients were put on kemantan. Study of the immune status of the patients who had ARVI and received kemantan demonstrated a significant increase in the formation of blasts and the concentration of T cells whose functional activity tended to rise. At the same time the above-mentioned indices remained intact or tended to drop in patients receiving no kemantan. The Soviet immunomodulator kemantan is recommended for a combined treatment of the pulmonary tuberculosis patients who had intercurrent viral infection to stimulate cellular immune defences and prevent an aggravation of the specific process.
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| Authors | N V Kossii, I S Khomenko, V Ia Gergert |
| Journal | Problemy tuberkuleza (Probl Tuberk) Issue 6 Pg. 23-6 ( 1991) ISSN: 0032-9533 [Print] Russia (Federation) |
| Vernacular Title | Lechenie immunodefitsitnykh sostoianiĭ, vyzvannykh perenesennoĭ virusnoĭ infektsieĭ, otechestvennym immunomoduliatorom kemantanom u bol'nykh tuberkulezom legkikh. |
| PMID | 1780303 (Publication Type: English Abstract, Journal Article) |
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