Neurocysticercosis treated with praziquantel. Long-term follow-up of a case.

Abstract

The Authors report a case of neurocysticercosis treated with praziquantel and ventriculoperitoneal shunt. The patient presented, at CAT, multiple intracranial calcifications and cysts located in the cerebral parenchyma, ventricular system and subarachnoid cisterns. Praziquantel was orally administered at a daily dosage of 50 mg/kg. Two 15 day cycles of therapy were administered with an interval of one month between them. No significant side effects were observed during the treatment. Serial follow-up CAT scans demonstrated a gradual decrease in size and, finally, total disappearance of the cystic lesions. No neurological disfunction was observed at the last follow-up examination 4 years after treatment.

• Authors: P Mancuso, I Chiaramonte, R Tropea
• Journal: Journal of neurosurgical sciences (J Neurosurg Sci) 1991 Jul-Sep Vol. 35 Issue 3 Pg. 157-60 ISSN: 0390-5616 [Print] Italy
• PMID: 1774596 (Publication Type: Journal Article)

Chemical References

• Praziquantel

Topics

• Brain Diseases (diagnostic imaging, drug therapy, surgery)
• Cerebrospinal Fluid Shunts
• Cysticercosis (diagnostic imaging, drug therapy, surgery)
• Drug Administration Schedule
• Female
• Follow-Up Studies
• Humans
• Middle Aged
• Peritoneal Cavity
• Praziquantel (administration & dosage, therapeutic use)
• Tomography, X-Ray Computed