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A simple and rapid method for quantifying 2-phenoxyethanol (2-PE) in Diphtheria, Tetanus and w-Pertussis (DTwP) vaccine.

AbstractThe authors developed a simple and rapid method for quantitation of 2-phenoxyethanol (2-PE) in DTwP vaccine based on reverse phase high performance liquid chromatography (HPLC). The method was simple and reproducible. The sensitivity of the assay was confirmed by spiking known amounts of 2-phenoxyethanol to the vaccine sample.
AuthorsBipin Sharma, Aditi Joseph, Anil Sood (Affiliation: Panacea Biotec Ltd., Lalru, Patiala 140501, Punjab, India. bipinsharma1 at yahoo.com)
JournalBiologicals : journal of the International Association of Biological Standardization (Biologicals) Vol. 36 Issue 1 Pg. 61-3 (Jan 2008) ISSN: 1045-1056 [Print] England
PMID17728142 (Publication Type: Journal Article)
Chemical References
  • Diphtheria-Tetanus-Pertussis Vaccine
  • Ethylene Glycols
  • phenoxyethanol
Topics
  • Calibration
  • Chromatography, High Pressure Liquid
  • Diphtheria-Tetanus-Pertussis Vaccine (chemistry)
  • Ethylene Glycols (analysis, chemistry)
  • Reproducibility of Results
  • Time Factors

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