| Abstract | This article opens with a brief history of pharmacologic treatment of schizophrenia. It then discusses the definition and treatment of treatment-resistant schizophrenia, with particular attention to clinical, biological and neuroimaging correlates, as well as the best treatment options, including the use of clozapine in patients who meet the definition of treatment-resistant schizophrenia. |
| Authors | Helio Elkis
(Affiliation: Department and Institute of Psychiatry, University of Sao Paulo Medical School (FMUSP), São Paulo, SP, Brazil. helkis at usp.br <helkis at usp.br>)
|
| Journal | The Psychiatric clinics of North America
(Psychiatr Clin North Am)
Vol. 30
Issue 3
Pg. 511-33
(Sep 2007)
ISSN: 1558-3147 United States |
| PMID | 17720034
(Publication Type: Journal Article, Review)
|
| Chemical References |
- Antipsychotic Agents
- Clozapine
|
| Topics |
- Antipsychotic Agents
(pharmacokinetics, pharmacology)
- Clozapine
(pharmacokinetics, pharmacology)
- Drug Resistance
- Humans
- Polypharmacy
- Schizophrenia
(drug therapy, radiography)
|
