| Abstract | The desire of reproduction is a true challenge for the physicians in charge of patients with chronic inflammatory disorders such as rheumatoid arthritis or other connective tissue diseases. It requires: 1) the strict evaluation of the potential risks of flare of the rheumatic disease because of the pregnancy; 2) the assessment of risks on pregnancy outcome and fetus development; 3) the management of the different anti-rheumatic agents in order to maintain optimal control of disease activity and avoid any teratogenic problem. Besides this, it clearly appears that inflammatory rheumatic diseases may have an impact on patients' fertility, which may be explained by different mechanisms, physical, psychological, hormonal or immunological. Moreover, some treatments may directly affect fertility, which may justify specific managements in order to preserve gonadic functions. |
| Authors | B Fautrel, M Benhamou
(Affiliation: Service de rhumatologie, groupe hospitalier de la Pitié-Salpêtrière, université Paris-VI-Pierre-et-Marie-Curie, 83, boulevard de l'Hôpital, 75651 Paris cedex 13, France. bruno.fautrel at psl.aphp.fr)
|
| Journal | Gynécologie, obstétrique & fertilité
(Gynecol Obstet Fertil)
Vol. 35
Issue 9
Pg. 848-52
(Sep 2007)
ISSN: 1297-9589 France |
| Vernacular Title | Rhumatisme inflammatoire chronique et procréation. |
| PMID | 17707673
(Publication Type: English Abstract, Journal Article)
|
| Topics |
- Antiphospholipid Syndrome
(complications)
- Arthritis, Rheumatoid
(complications)
- Female
- Fetal Development
- Humans
- Inflammation
(complications, etiology)
- Lupus Erythematosus, Systemic
(complications)
- Pregnancy
- Pregnancy Complications
(classification, epidemiology)
- Pregnancy Outcome
|
