Abstract |
We report a case of aseptic meningitis thought to be associated with chronic sulindac use in a patient with osteoarthritis. The patient was hospitalized with an acute onset of headache, nuchal rigidity, nausea, and blurred vision. Brain imaging was unremarkable and a lumbar puncture revealed a lymphocytic pleocytosis. No infectious source was identified. The patient reported taking sulindac over the past year, it was discontinued, and symptoms promptly resolved. This case underscores the importance of obtaining a thorough drug history in conjunction with the knowledge of causative medications associated with aseptic meningitis. Given the widespread use of nonsteroidal anti-inflammatory drugs, clinicians must recognize that aseptic meningitis is a possible adverse effect of these medications.
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Authors | Erin C Callen, Chelsea O Church, Manish Patel, Tiffany L Sikes |
Journal | Rheumatology international
(Rheumatol Int)
Vol. 28
Issue 4
Pg. 391-3
(Feb 2008)
ISSN: 0172-8172 [Print] Germany |
PMID | 17703306
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Anti-Inflammatory Agents, Non-Steroidal
- Sulindac
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Topics |
- Aged
- Anti-Inflammatory Agents, Non-Steroidal
(adverse effects)
- Humans
- Male
- Meningitis, Aseptic
(chemically induced)
- Osteoarthritis
(drug therapy)
- Risk Factors
- Sulindac
(adverse effects)
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