Abstract | BACKGROUND AND PURPOSE: Five to 60% of coiled brain aneurysms recanalize, generally because of coil compaction. In vitro exclusive use of complex-shaped coils allows better packing of the aneurysmal sac and the neck as compared with helical coils. We report a single-center, prospective study using complex coils. Safety, packing density, and recanalization rate were evaluated. MATERIALS AND METHODS: Seventy-seven aneurysms were embolized using complex coils alone. Aneurysms had a volume of 265 mm3 (diameter: 7.1+/-3.3 mm) and a neck size of 4.1+/-1.8 mm (range: 1.5-12 mm). Average follow-up available in 31 patients was 10.5+/-7.6 months (range: 3-36 months). Primary angiographic endpoints included aneurysmal recanalization and (re) rupture. Primary adverse events included stroke or death. RESULTS: Complete or near-complete occlusion was achieved in all of the aneurysms but required balloon assistance in 24.6%. The packing density was computed as 37%+/-13%. No rerupture was observed during the follow-up interval. Recanalization was seen in 4 (12.9%) of 31. Two basilar tip aneurysms underwent a safe and complete recoiling. Periprocedural nondevice-related neurologic deficits were seen in 2 (2.9%) of 69 patients. CONCLUSIONS: The use of complex-shaped coils allows higher packing density, which may improve the recanalization rate. Basilar tip aneurysms remain a challenge.
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Authors | A K Wakhloo, M J Gounis, J S Sandhu, N Akkawi, A E Schenck, I Linfante |
Journal | AJNR. American journal of neuroradiology
(AJNR Am J Neuroradiol)
Vol. 28
Issue 7
Pg. 1395-400
(Aug 2007)
ISSN: 0195-6108 [Print] United States |
PMID | 17698550
(Publication Type: Clinical Trial, Journal Article)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Cerebral Angiography
- Child
- Embolization, Therapeutic
(instrumentation, methods)
- Equipment Design
- Female
- Humans
- Intracranial Aneurysm
(diagnostic imaging, therapy)
- Male
- Middle Aged
- Platinum
- Treatment Outcome
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