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Complex-shaped platinum coils for brain aneurysms: higher packing density, improved biomechanical stability, and midterm angiographic outcome.

AbstractBACKGROUND AND PURPOSE:
Five to 60% of coiled brain aneurysms recanalize, generally because of coil compaction. In vitro exclusive use of complex-shaped coils allows better packing of the aneurysmal sac and the neck as compared with helical coils. We report a single-center, prospective study using complex coils. Safety, packing density, and recanalization rate were evaluated.
MATERIALS AND METHODS:
Seventy-seven aneurysms were embolized using complex coils alone. Aneurysms had a volume of 265 mm3 (diameter: 7.1+/-3.3 mm) and a neck size of 4.1+/-1.8 mm (range: 1.5-12 mm). Average follow-up available in 31 patients was 10.5+/-7.6 months (range: 3-36 months). Primary angiographic endpoints included aneurysmal recanalization and (re)rupture. Primary adverse events included stroke or death.
RESULTS:
Complete or near-complete occlusion was achieved in all of the aneurysms but required balloon assistance in 24.6%. The packing density was computed as 37%+/-13%. No rerupture was observed during the follow-up interval. Recanalization was seen in 4 (12.9%) of 31. Two basilar tip aneurysms underwent a safe and complete recoiling. Periprocedural nondevice-related neurologic deficits were seen in 2 (2.9%) of 69 patients.
CONCLUSIONS:
The use of complex-shaped coils allows higher packing density, which may improve the recanalization rate. Basilar tip aneurysms remain a challenge.
AuthorsA K Wakhloo, M J Gounis, J S Sandhu, N Akkawi, A E Schenck, I Linfante
JournalAJNR. American journal of neuroradiology (AJNR Am J Neuroradiol) Vol. 28 Issue 7 Pg. 1395-400 (Aug 2007) ISSN: 0195-6108 [Print] United States
PMID17698550 (Publication Type: Clinical Trial, Journal Article)
Chemical References
  • Platinum
Topics
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Cerebral Angiography
  • Child
  • Embolization, Therapeutic (instrumentation, methods)
  • Equipment Design
  • Female
  • Humans
  • Intracranial Aneurysm (diagnostic imaging, therapy)
  • Male
  • Middle Aged
  • Platinum
  • Treatment Outcome

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