Abstract | BACKGROUND: Optimal chemotherapeutic regimen in thymic carcinoma remains uncertain and the efficacy of second line chemotherapy has not been established either. PATIENTS AND METHODS: RESULT: Two patients achieved partial responses. Although another two patients showed a significant reduction of the primary thoracic lesion, the appearance of a new lesion was found in one and a metastatic lesion was unchanged in the other. Neutropenia over grade 3 was observed in all patients but none of the patients developed serious infections. There were no severe non-hematological toxicities, including diarrhea. CONCLUSION:
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Authors | Shintaro Kanda, Tomonobu Koizumi, Yoshimichi Komatsu, Sumiko Yoshikawa, Mitsuyo Okada, Orie Hatayama, Masanori Yasuo, Kenji Tsushima, Kazuhisa Urushihata, Keishi Kubo, Mari Sasabayashi, Akemi Takamizawa |
Journal | Anticancer research
(Anticancer Res)
2007 Jul-Aug
Vol. 27
Issue 4C
Pg. 3005-8
ISSN: 0250-7005 [Print] Greece |
PMID | 17695487
(Publication Type: Journal Article)
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Chemical References |
- Vincristine
- Irinotecan
- Doxorubicin
- Cyclophosphamide
- Carboplatin
- Cisplatin
- Camptothecin
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Topics |
- Adult
- Aged
- Antineoplastic Combined Chemotherapy Protocols
(administration & dosage, therapeutic use)
- Camptothecin
(adverse effects, analogs & derivatives)
- Carboplatin
(administration & dosage)
- Cisplatin
(administration & dosage)
- Cyclophosphamide
(administration & dosage)
- Doxorubicin
(administration & dosage)
- Female
- Humans
- Irinotecan
- Male
- Middle Aged
- Retrospective Studies
- Survival Rate
- Thymus Neoplasms
(drug therapy)
- Vincristine
(administration & dosage)
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