Abstract | BACKGROUND & AIMS: This study investigated the effects of nutritional support on postoperative complications, in relation with demographic and nutritional factors, intraoperative factors, type and routes of nutritional regimens. METHODS: RESULTS: Major and minor complications occurred in 101 (7.2%) and 446 (31.6%) patients, respectively. Factors correlated with postoperative complications at multivariate analysis were pancreatic surgery, (p<0.001), advanced age (p=0.002), weight loss (p=0.019), low serum albumin (p=0.019) and nutritional support (p=0.001). Nutritional support reduced morbidity versus SIF with an increasing protective effect of TPN, EN, and IEEN. This effect remained valid regardless the severity of risk factors identified at the multivariate analysis and it was more evident by considering infectious complications only. CONCLUSIONS: Pancreatic surgery, advanced age, weight loss and low serum albumin are independent risk factors for the onset of postoperative complications. Nutritional support, particularly IEEN, significantly reduced postoperative morbidity.
|
Authors | Federico Bozzetti, Luca Gianotti, Mario Braga, Valerio Di Carlo, Luigi Mariani |
Journal | Clinical nutrition (Edinburgh, Scotland)
(Clin Nutr)
Vol. 26
Issue 6
Pg. 698-709
(Dec 2007)
ISSN: 1532-1983 [Electronic] England |
PMID | 17683831
(Publication Type: Journal Article)
|
Chemical References |
|
Topics |
- Age Factors
- Aged
- Colorectal Neoplasms
(mortality, surgery, therapy)
- Enteral Nutrition
- Female
- Fluid Therapy
- Gastrointestinal Neoplasms
(mortality, surgery, therapy)
- Humans
- Immune System
(physiology)
- Male
- Middle Aged
- Morbidity
- Multivariate Analysis
- Nutritional Status
- Nutritional Support
(methods)
- Pancreatic Neoplasms
(mortality, surgery, therapy)
- Parenteral Nutrition, Total
- Perioperative Care
(methods)
- Postoperative Care
(methods)
- Postoperative Complications
(epidemiology)
- Risk Factors
- Serum Albumin
(analysis)
- Stomach Neoplasms
(mortality, surgery, therapy)
- Survival Analysis
- Time Factors
- Treatment Outcome
- Weight Loss
|