Abstract |
Immune reconstitution inflammatory syndrome (IRIS) is an unusual inflammatory reaction due to infectious and non-infectious causes occurring in human Immunodeficiency virus (HIV)-infected patients. IRIS occurs after the initiation of antiretroviral therapy. There are no reports of type I lepra reaction due to IRIS in published literature from India. We report two cases of HIV-infected males who presented with borderline tuberculoid leprosy in type 1 reaction after the initiation of highly active antiretroviral treatment ( HAART). Case 1 presented with multiple, tender, erythematous and hypoesthetic plaques on the trunk and extremities after 3 months of antiretroviral therapy. In case 2, type I lepra reaction was observed 2 months after the initiation of HAART.
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Authors | Vidya Kharkar, Urmila H Bhor, Sunanda Mahajan, Uday Khopkar |
Journal | Indian journal of dermatology, venereology and leprology
(Indian J Dermatol Venereol Leprol)
2007 Jul-Aug
Vol. 73
Issue 4
Pg. 253-6
ISSN: 0973-3922 [Electronic] United States |
PMID | 17675735
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- AIDS-Related Opportunistic Infections
(chemically induced)
- Adult
- Antiretroviral Therapy, Highly Active
(adverse effects)
- CD4 Lymphocyte Count
- HIV Infections
(complications, immunology)
- Humans
- Hypersensitivity
(diagnosis, etiology)
- Leprostatic Agents
(therapeutic use)
- Leprosy, Borderline
(chemically induced, diagnosis)
- Leprosy, Tuberculoid
(chemically induced, diagnosis)
- Male
- Skin
(pathology)
- Syndrome
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