| Abstract | The management of hormone-dependent male breast cancer is insufficiently understood by practicing oncologists. This article provides a review of the endocrine profile of male breast cancer, and outlines the differences between hormone-dependent female and male breast cancers. A concise review of the past, present, and possible future management of hormone-dependent male breast cancer is presented. For a better understanding of this disease, more information on the natural history and biological behaviors of patients with male breast cancer is needed. This could be accomplished by the development of a specific multi-institutional tumor registry and execution of prospective clinical trials. |
| Authors | Nikolay V Dimitrov, Philomena Colucci, Sunil Nagpal
(Affiliation: Michigan State University, B413 Clinical Center, East Lansing, MI 48824, USA. dimitrov at msu.edu)
|
| Journal | The oncologist
(Oncologist)
Vol. 12
Issue 7
Pg. 798-807
(Jul 2007)
ISSN: 1083-7159 United States |
| PMID | 17673611
(Publication Type: Journal Article, Review)
|
| Chemical References |
- Antineoplastic Agents, Hormonal
- Estrogens
- Receptors, Estrogen
- Selective Estrogen Receptor Modulators
- Tamoxifen
- Testosterone
|
| Topics |
- Antineoplastic Agents, Hormonal
(pharmacology, therapeutic use)
- Breast Neoplasms, Male
(drug therapy, metabolism)
- Endocrine Glands
(drug effects, metabolism)
- Estrogens
(metabolism)
- Female
- Humans
- Male
- Neoplasms, Hormone-Dependent
(drug therapy, metabolism)
- Receptors, Estrogen
(physiology, therapeutic use)
- Selective Estrogen Receptor Modulators
(pharmacology, therapeutic use)
- Tamoxifen
(pharmacology, therapeutic use)
- Testosterone
(metabolism)
|
