HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Case reports: efalizumab-associated lymphoproliferative disease.

Abstract
Efalizumab is an immunosuppressive agent that has been approved for the treatment of psoriasis. There has been mounting evidence that efalizumab may be associated with lymphoma/malignancy development. To our knowledge, this is the first documented case of a patient who developed Epstein Barr Virus-associated large B cell lymphoma after treatment with efalizumab for psoriasis. As immunosuppressive medications such as efalizumab get increasingly prescribed, the likelihood of seeing various malignancies will increase. Thus, physicians need to have a high index of suspicion for malignancy in patients on immunosuppressive medications like efalizumab.
AuthorsSatya Bommakanti, Amol Patil, Camellia Eshoa, Christopher R Chitambar
JournalJournal of drugs in dermatology : JDD (J Drugs Dermatol) Vol. 6 Issue 6 Pg. 646-8 (Jun 2007) ISSN: 1545-9616 [Print] United States
PMID17668531 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Immunosuppressive Agents
  • efalizumab
Topics
  • Antibodies, Monoclonal (adverse effects, therapeutic use)
  • Antibodies, Monoclonal, Humanized
  • Herpesvirus 4, Human (growth & development)
  • Humans
  • Immunosuppressive Agents (adverse effects, therapeutic use)
  • Lymphoma, B-Cell (chemically induced, diagnosis, virology)
  • Lymphoma, Large B-Cell, Diffuse (chemically induced, diagnosis, virology)
  • Lymphoproliferative Disorders (chemically induced, diagnosis)
  • Male
  • Middle Aged
  • Psoriasis (drug therapy)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: