HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Pradefovir, a liver-targeted prodrug of adefovir against HBV infection.

Abstract
Metabasis Therapeutics Inc (previously Ribapharm Inc) is developing pradefovir, an oral liver-targeting prodrug of adefovir developed using its HepDirect technology, for the potential treatment of HBV infection. Phase II clinical trials of pradefovir have been completed.
AuthorsHans L Tillmann
JournalCurrent opinion in investigational drugs (London, England : 2000) (Curr Opin Investig Drugs) Vol. 8 Issue 8 Pg. 682-90 (Aug 2007) ISSN: 1472-4472 [Print] England
PMID17668370 (Publication Type: Journal Article)
Chemical References
  • Antiviral Agents
  • Organophosphonates
  • Organophosphorus Compounds
  • Prodrugs
  • adefovir
  • pradefovir
  • Adenine
Topics
  • Adenine (analogs & derivatives, chemical synthesis, pharmacokinetics, therapeutic use)
  • Antiviral Agents (chemical synthesis, pharmacokinetics, therapeutic use)
  • Clinical Trials, Phase I as Topic
  • Clinical Trials, Phase II as Topic
  • Drug Delivery Systems
  • Hepatitis B, Chronic (drug therapy)
  • Humans
  • Liver (metabolism)
  • Organophosphonates (pharmacokinetics, therapeutic use)
  • Organophosphorus Compounds (chemical synthesis, pharmacokinetics, therapeutic use)
  • Prodrugs (chemical synthesis, pharmacokinetics, therapeutic use)
  • Structure-Activity Relationship

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: