[The effectiveness of fenspiride in the treatment of patients with chronic obstructive pulmonary disease].

Abstract

The purpose of the study was to assess the effectiveness and safety of long-term application of fenspiride, an anti-inflammatory drug, in patients with chronic obstructive pulmonary disease (COPD) under outpatient conditions. The drug was studied on 24 COPD patients. Fenspiride application resulted in improvement in bronchoobstructive syndrome and external respiration parameters, as well as a significant increase in exercise tolerance. In patients with stable stage I COPD, the use of fenspiride as a part of therapeutic regimen leads to better clinical results than in stage II patients. Long-term application of fenspiride in medium therapeutic doses under outpatient conditions is associated with positive clinical effects and leads to significant improvement in quality of life.

• Authors: S I Butorov, V I Muntianu
• Journal: Klinicheskaia meditsina (Klin Med (Mosk)) Vol. 85 Issue 5 Pg. 43-7 ( 2007) ISSN: 0023-2149 [Print] Russia (Federation)
• PMID: 17665604 (Publication Type: English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Anti-Inflammatory Agents
• Bronchodilator Agents
• Spiro Compounds
• fenspiride

Topics

• Adult
• Aged
• Ambulatory Care
• Anti-Inflammatory Agents (therapeutic use)
• Bronchodilator Agents (therapeutic use)
• Female
• Humans
• Male
• Middle Aged
• Pulmonary Disease, Chronic Obstructive (drug therapy, physiopathology)
• Quality of Life
• Severity of Illness Index
• Spiro Compounds (therapeutic use)
• Treatment Outcome