Osteomyelitis: sensitivity of 0.064 T MRI, three-phase bone scanning and indium scanning with biopsy proof.

Abstract

We compared the ability of magnetic resonance imaging (MRI) using a 0.064 T permanent magnet, three-phase bone scanning, and indium-labeled white blood cell (111In-WBC) scanning, to diagnose osteomyelitis. Twenty-three patients underwent biopsy. All patients were examined at presentation with all three modalities. Sensitivities for each modality were calculated using biopsy as a gold standard. The results were 72% for MRI, 68% for bone scan, and 45% for 111In-WBC. Specificities were not calculated because of lack of negative biopsies. MRI was as sensitive as bone scanning in the diagnosis of osteomyelitis. All modalities had lower than previously reported sensitivities for imaging osteomyelitis.

• Authors: M R Williamson, R W Quenzer, R D Rosenberg, A J Meholic, B Eisenberg, M C Espinosa, M F Hartshorne
• Journal: Magnetic resonance imaging (Magn Reson Imaging) Vol. 9 Issue 6 Pg. 945-8 ( 1991) ISSN: 0730-725X [Print] Netherlands
• PMID: 1766320 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Indium Radioisotopes
• Technetium Tc 99m Medronate

Topics

• Biopsy
• Bone and Bones (diagnostic imaging, pathology)
• Evaluation Studies as Topic
• Humans
• Indium Radioisotopes
• Leukocytes
• Magnetic Resonance Imaging (methods)
• Osteomyelitis (diagnosis, epidemiology)
• Prospective Studies
• Radionuclide Imaging
• Sensitivity and Specificity
• Technetium Tc 99m Medronate