[Effects of nicardipine on the functional state of the liver in patients with ischemic heart disease].

Abstract

Hepatic function was studied in 31 patients with coronary heart disease before and after treatment with nicardipine. Clinical and biochemical findings (enhanced gamma-glutamate transferase and high cholesterol, hepatobiliary syndrome) provide evidence for hepatic function disturbance associated with coronary heart disease. Nicardipine produced a good subjective response, the attenuation of hepatobiliary syndrome. Biochemical indices did not change.

• Authors: L G Makeeva, S D Svetova, A I Martynov, A L Vertkin, V V Makarovskiĭ, Iu A Shafranskiĭ
• Journal: Klinicheskaia meditsina (Klin Med (Mosk)) Vol. 69 Issue 10 Pg. 42-4 (Oct 1991) ISSN: 0023-2149 [Print] Russia (Federation)
• Vernacular Title: Vliianie nikardipina na funktsional'noe sostoianie pecheni u bol'nykh ishemicheskoĭ bolezn'iu serdtsa.
• PMID: 1766214 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Nicardipine

Topics

• Adult
• Coronary Disease (drug therapy, physiopathology)
• Humans
• Liver (drug effects, physiopathology)
• Liver Function Tests
• Middle Aged
• Nicardipine (pharmacology, therapeutic use)