Nitinol stenting for treatment of ''below-the-knee'' critical limb ischemia: 1-year angiographic outcome after Xpert stent implantation.

Abstract

AIM:

We investigated the efficacy of Xpert (Abbott Vascular Devices) nitinol stents for the treatment of infrapopliteal lesions in patients with critical limb ischemia (CLI).

METHODS:

Between May and October 2005, 47 CLI patients (35 men, mean age 73 years) received 67 Xpert stents for the treatment of 58 infrapopliteal lesions in 51 limbs; 43 patients (84.3%) were classified in Rutherford Category 4 and 8 (15.7%) in Category 5. Clinical examination and quantitative vascular analysis (QVA) were performed before and after the intervention and at 12-months follow-up. The primary endpoint was defined as 1-year angiographic binary restenosis rate (>50% stenosis on QVA); the secondary endpoints were 1-year primary patency and limb salvage rate.

RESULTS:

QVA after 1 year showed a binary restenosis rate of 20.45%. Kaplan-Meier analysis revealed 1-year primary patency and limb salvage rates of 76.3% and 95.9%, respectively. The limb salvage rate was significantly better in patients with proximal below-the-knee (BTK) than in those with mid-section or distal lesions (100% vs 81.8%; P=0.0071).

CONCLUSION:

Our results suggest that treatment with nitinol Xpert stents in CLI patients is effective and yields satisfactory angiographic and clinical outcome.

• Authors: M Bosiers, K Deloose, J Verbist, P Peeters
• Journal: The Journal of cardiovascular surgery (J Cardiovasc Surg (Torino)) Vol. 48 Issue 4 Pg. 455-61 (Aug 2007) ISSN: 0021-9509 [Print] Italy
• PMID: 17653005 (Publication Type: Controlled Clinical Trial, Journal Article)

Chemical References

• Alloys
• nitinol

Topics

• Aged
• Alloys
• Angioplasty, Balloon
• Equipment Design
• Female
• Follow-Up Studies
• Humans
• Ischemia (diagnostic imaging, therapy)
• Leg (blood supply)
• Male
• Prospective Studies
• Radiography
• Stents
• Time Factors
• Treatment Outcome