Abstract | BACKGROUND: Metallic stents are a therapeutic option for patients with malignant GI obstruction. OBJECTIVE: Our purpose was to evaluate the clinical effectiveness of a self-expandable metallic stent in 213 patients with malignant gastroduodenal obstruction and to identify prognostic factors associated with clinical outcomes. DESIGN: Prospective cohort study. SETTING: Single tertiary referral university hospital. PATIENTS: Two hundred thirteen consecutive patients with symptomatic malignant gastric outlet or duodenal obstruction from 2001 to 2005. INTERVENTIONS: MAIN OUTCOME MEASUREMENTS: Prospective data collection focused on technical and clinical success, complications, and prognostic factors associated with stent patency. RESULTS: Technical and clinical success were achieved in 94% and 94% of the patients, respectively, and the complication rate was 21%. The median and mean survival periods were 99 (95% CI, 78-121) and 159 days (95% CI, 116-203). The median and mean stent patency periods were 270 (95% CI, 234-413) and 324 days (95% CI, 128-412). With use of the multivariate Cox proportional hazard model, chemotherapy after stent placement (odds ratio, 0.19; 95% CI, 0.08-0.46; P < .001) was significantly associated with an increase in the maintenance of stent patency. LIMITATIONS: Single-center experience and the lack of a control group. CONCLUSIONS:
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Authors | Jin Hyoung Kim, Ho-Young Song, Ji Hoon Shin, Eugene Choi, Tae Won Kim, Hwoon-Yong Jung, Gin Hyug Lee, Sung Koo Lee, Myung-Hwan Kim, Min-Hee Ryu, Yoon-Koo Kang, Byung Sik Kim, Jeong Hwan Yook |
Journal | Gastrointestinal endoscopy
(Gastrointest Endosc)
Vol. 66
Issue 2
Pg. 256-64
(Aug 2007)
ISSN: 0016-5107 [Print] United States |
PMID | 17643698
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Alloys
- Duodenal Obstruction
(etiology, surgery)
- Endoscopy, Gastrointestinal
- Female
- Fluoroscopy
- Gastric Outlet Obstruction
(etiology, surgery)
- Gastrointestinal Neoplasms
(complications)
- Humans
- Male
- Middle Aged
- Palliative Care
- Stents
(adverse effects)
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