Pleuropulmonary blastoma: transition from type I (cystic) to type III (solid).

Abstract

Pleuropulmonary blastoma is a unique dysontogenetic neoplasm of childhood that appears as a pulmonary and/or pleural-based mass, and is characterised histologically by a primitive, variably mixed blastematic and sarcomatous appearance. We report a 12-month-old female child who was operated for a lung cyst at the age of six months and postoperative histopathology was suggestive of type I pleuropulmonary blastoma (PPB). She presented to us at the age of twelve months with a huge mass over the left chest wall and axilla, histopathological examination of which was type III PPB. Partial removal of the lung cyst led to transition from type I to type III PPB in a short span of a few months. Complete surgical removal followed by adjuvant chemotherapy is needed for a better outcome in type I PPB.

• Authors: R Shivastava, A Saha, B Mehera, P Batra, N M Gagane
• Journal: Singapore medical journal (Singapore Med J) Vol. 48 Issue 7 Pg. e190-2 (Jul 2007) ISSN: 2737-5935 [Electronic] India
• PMID: 17609812 (Publication Type: Case Reports, Journal Article)

Topics

• Fatal Outcome
• Female
• Humans
• Infant
• Lung Neoplasms (classification, pathology, surgery)
• Pulmonary Blastoma (classification, pathology, surgery)