[Clinical research of effect of Yishen Yangnao capsule on vascular dementia].

Abstract

OBJECTIVE:

To find a good way to diagnose VD, value the effect of Yishen Yangnao capsule on VD and try to find some rules of changes in Chinese medicine syndromes.

METHOD:

Patients were randomly divided into treating group and western medicine comparison group. It's the phase III clinical research of Rishen Yangnao capsule curing VD, judging the validity and security of it, using dukexi slice as comparison drug. Some of the patients did the examination of P300.

RESULT:

The total validity of Yishen Yangnao capsule is 56.3% (contract team is 60.0%). The improve rate of ADL is 0.1069% (contract team is 0.1134%). The scores of Chinese medicine syndrome descend.

CONCLUSION:

Yishen Yangnao capsule has the same effect as dukexi slice in curing VD at the side of intelligence situation and life ability.

• Authors: Wen-jie Xu, Zong-heng Li, Yong-mei Shi, Yi-huai Zou
• Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (Zhongguo Zhong Yao Za Zhi) Vol. 32 Issue 8 Pg. 732-5 (Apr 2007) ISSN: 1001-5302 [Print] China
• PMID: 17608233 (Publication Type: Clinical Trial, Phase III, English Abstract, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Capsules
• Drug Combinations
• Drugs, Chinese Herbal
• Neuroprotective Agents
• yishen yangnao
• Yohimbine
• almitrine, raubasine drug combination
• Almitrine

Topics

• Activities of Daily Living
• Aged
• Almitrine (therapeutic use)
• Capsules
• Dementia, Vascular (drug therapy, physiopathology)
• Drug Combinations
• Drugs, Chinese Herbal (isolation & purification, therapeutic use)
• Event-Related Potentials, P300
• Female
• Humans
• Male
• Medicine, Chinese Traditional (methods)
• Middle Aged
• Neuroprotective Agents (isolation & purification, therapeutic use)
• Phytotherapy
• Treatment Outcome
• Yohimbine (therapeutic use)