PET Scans are most often used for detecting
cancer and other malignant
tumors because for most of them,
glucose uptake is higher than in normal tissues. However, in
mesothelioma, our study showed excessive deposits of
Asbestos of 0.5 mg BDORT units, and markedly reduced
Glucose uptake of less than 1/30 of normal tissue. As a consequence, the authors found that, in the location where there is a
mesothelioma, distinctive dark black areas much darker than any normal tissue appear in the PET Scan. Therefore, a PET Scan taken parallel to the front & back of the chest wall often shows pitch-black areas on the chest wall of the patient, located on the ribs in the case of large black areas and between the ribs in the case of small black areas. If the amount of
Asbestos in these areas is found to be very high in the same location where the
glucose uptake is very low, one can suspect the presence of
mesothelioma, which is often found at the inner wall of the chest cavity or the peritoneum in the abdomen with significantly increased Osteopontine (about 350-400 times that of normal tissue) and very significant increase in
Gastrin Releasing
Peptides (more than 1200 times that of normal tissue). In some patients, the only abnormal blood chemistry detected was abnormally increased
Pro-Gastrin Releasing
Peptide. This dark black area on the PET Scan image taken parallel to front and back of chest wall (with marked increase in
asbestos,
Gastrin-Releasing Peptide, & Osteopontine and marked decrease in
glucose uptake in the pathological tissue) can be considered a characteristic finding for the diagnosis of
mesothelioma.