Cryptosporidium parvum-associated sclerosing cholangitis in a liver transplant patient.

Abstract

Cryptosporidium parvum causes severe long-standing diarrhea in immunocompromised patients. Sclerosing cholangitis caused by C. parvum is a rare complication in transplant recipients. We report herein the presentation of Cryptosporidium-associated cholangitis in an adult liver transplant patient diagnosed by liver biopsy. The patient improved on treatment with azithromycin and paromomycin.

• Authors: C M Denkinger, P Harigopal, P Ruiz, L M Dowdy
• Journal: Transplant infectious disease : an official journal of the Transplantation Society (Transpl Infect Dis) Vol. 10 Issue 2 Pg. 133-6 (Apr 2008) ISSN: 1399-3062 [Electronic] Denmark
• PMID: 17605744 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Paromomycin
• Azithromycin

Topics

• Animals
• Azithromycin (therapeutic use)
• Cholangitis, Sclerosing (drug therapy, parasitology)
• Cryptosporidiosis (complications)
• Cryptosporidium parvum (pathogenicity)
• Humans
• Immunocompromised Host
• Liver Transplantation (adverse effects, immunology)
• Male
• Middle Aged
• Paromomycin (therapeutic use)
• Treatment Outcome