Abstract |
The hemorrhagic side effects associated with the use of clopidogrel are within the acceptable range and occur mainly at skin or gastrointestinal sites. We report a case of spontaneous spinal epidural hematoma (SSEH) in a 60-yr-old woman who was treated with clopidogrel for frequent transient ischemic attacks. To our knowledge, this is the second reported case of clopidogrel-induced SSEH. The patient's symptoms and past history of clopidogrel use suggested the diagnosis and made the procedure proceed quickly to operate SSEH 9 hr after the onset of paraplegia. The outcome was excellent. Therefore, with the popularity of antiplatelet prescription, physicians should keep in mind and urgently treat this unusual but critical side effect.
|
Authors | Jae Hoon Sung, Jae Taek Hong, Byung Chul Son, Sang Won Lee |
Journal | Journal of Korean medical science
(J Korean Med Sci)
Vol. 22
Issue 3
Pg. 577-9
(Jun 2007)
ISSN: 1011-8934 [Print] Korea (South) |
PMID | 17596676
(Publication Type: Case Reports, Journal Article)
|
Chemical References |
- Platelet Aggregation Inhibitors
- Clopidogrel
- Ticlopidine
|
Topics |
- Aged
- Brain
(pathology)
- Cerebral Angiography
- Clopidogrel
- Female
- Hematoma, Epidural, Spinal
(chemically induced)
- Humans
- Ischemia
(drug therapy)
- Magnetic Resonance Imaging
- Platelet Aggregation Inhibitors
(adverse effects)
- Ticlopidine
(adverse effects, analogs & derivatives)
- Time Factors
- Treatment Outcome
|