Invasive infections due to Saccharomyces boulardii (Ultra-levure).

Abstract

(1) Saccharomyces boulardii, a yeast closely related to Saccharomyces cerevisiae, is marketed in France for adjuvant treatment of diarrhoea, although it has no proven efficacy. (2) Invasive infections due to Saccharomyces boulardii have occurred. Most of the patients had gastrointestinal disorders, an intravenous catheter, or ongoing antibiotic treatment. Only 25% of patients were immunosuppressed. (3) Unless the value of this type of treatment based on live microorganisms is demonstrated in methodologically sound clinical trials, it is best to avoid prescribing it to fragile patients.

• Journal: Prescrire international (Prescrire Int) Vol. 16 Issue 89 Pg. 110 (Jun 2007) ISSN: 1167-7422 [Print] France
• PMID: 17582930 (Publication Type: Journal Article)

Chemical References

• Anti-Bacterial Agents
• Antidiarrheals
• Antifungal Agents

Topics

• Anti-Bacterial Agents (adverse effects)
• Antidiarrheals (therapeutic use)
• Antifungal Agents
• Diarrhea (therapy)
• France
• Fungemia (etiology)
• Gastrointestinal Diseases (prevention & control)
• Humans
• Saccharomyces (pathogenicity)
• Yeast, Dried (adverse effects, therapeutic use)