Cystic endocrine tumor of the pancreas.

Abstract

A large cystic tumor in the pancreatic body was found incidentally in an 85-yr-old male. A distal pancreatectomy was performed after a diagnosis of cystadenocarcinoma. Microscopic examination of the resected specimen revealed a pancreatic cystic endocrine tumor; however, this tumor produced no symptoms. Immunohistochemical studies of the tumor cells showed positivity for gastrin, neuron-specific enolase, chromogranin A, and synaptophysin, and two cell types of neurosecretory granules were recognized in electron-microscopic studies. Although endocrine tumors of the pancreas are usually solid and cystic change occurs only rarely, such tumors should be considered in the differential diagnosis of patients who have a cystic lesion in the pancreas.

• Authors: T Nojima, T Kojima, H Kato, K Inoue, K Nagashima
• Journal: International journal of pancreatology : official journal of the International Association of Pancreatology (Int J Pancreatol) Vol. 10 Issue 1 Pg. 65-72 (Sep 1991) ISSN: 0169-4197 [Print] United States
• PMID: 1757731 (Publication Type: Case Reports, Journal Article)

Chemical References

• Pancreatic Hormones

Topics

• Aged
• Aged, 80 and over
• Diagnosis, Differential
• Humans
• Immunohistochemistry
• Male
• Microscopy, Electron
• Pancreatic Hormones (metabolism)
• Pancreatic Neoplasms (diagnosis, metabolism, pathology)
• Paraneoplastic Endocrine Syndromes (diagnosis, metabolism, pathology)