Abstract | INTRODUCTION:
Deep brain stimulation (DBS) at the internal globus pallidus (GPi) is an effective treatment for some patients with medically refractory torsion dystonia. In this article, we review the results of pallidal DBS surgery in children with dystonia. Details of the DBS procedure and programming of the DBS devices are discussed. DISCUSSION: Pallidal DBS is most effective in patients with primary generalized dystonia. Children and adolescents possessing the DYT1 gene mutation may respond best of all. The presence of static dystonic postures and/or fixed orthopedic contractures may limit the functional response to DBS and may require additional surgery. CONCLUSION:
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Authors | Ron L Alterman, Michele Tagliati |
Journal | Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
(Childs Nerv Syst)
Vol. 23
Issue 9
Pg. 1033-40
(Sep 2007)
ISSN: 0256-7040 [Print] Germany |
PMID | 17551738
(Publication Type: Journal Article, Review)
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Topics |
- Deep Brain Stimulation
(methods)
- Disability Evaluation
- Dystonia Musculorum Deformans
(classification, pathology, therapy)
- Humans
- Pediatrics
- Severity of Illness Index
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