The effects of fine-needle biopsy on thyroid hormone levels.

Abstract

OBJECTIVE:

Our study aim was to investigate the effects of fine-needle biopsy used for thyroid nodules on serum thyroid hormone levels.

STUDY DESIGN:

A total of 25 patients who had solid nodules of the thyroid gland and normal thyroid hormone levels underwent diagnostic fine-needle biopsy for a nodule of the thyroid gland.

METHODS:

Venous blood samples were drawn from the cases for measurement of serum total T(3) and T(4), free T(3) and T(4), thyroid-stimulating hormone, and thyroglobulin levels before, immediately after, and 30 minutes after the initial biopsy.

RESULTS:

Total T(3) and thyroglobulin levels were found to be significantly higher immediately and 30 minutes following fine-needle aspiration biopsy, compared to the baseline levels (P<0.05).

CONCLUSION:

Preliminary data suggest that thyroid hormone levels show a mean increase of about 20% immediately after fine-needle aspiration.

SIGNIFICANCE:

The implication of this finding on patient care should be determined on an individual basis.

• Authors: H Cengiz Alpay, Turgut Kalidag, Erol Keles, Irfan Kaygusuz, Sinasi Yalcin, Zeliha Kapusuz
• Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery (Otolaryngol Head Neck Surg) Vol. 136 Issue 6 Pg. 942-5 (Jun 2007) ISSN: 0194-5998 [Print] England
• PMID: 17547984 (Publication Type: Journal Article)

Chemical References

• Thyroid Hormones
• Triiodothyronine
• Thyrotropin
• Thyroglobulin
• Thyroxine

Topics

• Adult
• Aged
• Biopsy, Fine-Needle
• Diagnosis, Differential
• Female
• Humans
• Male
• Middle Aged
• Reference Values
• Thyroglobulin (blood)
• Thyroid Gland (pathology)
• Thyroid Hormones (blood)
• Thyroid Nodule (pathology)
• Thyrotropin (blood)
• Thyroxine (blood)
• Triiodothyronine (blood)