| Abstract | OBJECTIVE: Our study aim was to investigate the effects of fine-needle biopsy used for thyroid nodules on serum thyroid hormone levels. STUDY DESIGN: A total of 25 patients who had solid nodules of the thyroid gland and normal thyroid hormone levels underwent diagnostic fine-needle biopsy for a nodule of the thyroid gland. METHODS: Venous blood samples were drawn from the cases for measurement of serum total T(3) and T(4), free T(3) and T(4), thyroid-stimulating hormone, and thyroglobulin levels before, immediately after, and 30 minutes after the initial biopsy. RESULTS: Total T(3) and thyroglobulin levels were found to be significantly higher immediately and 30 minutes following fine-needle aspiration biopsy, compared to the baseline levels (P<0.05). CONCLUSION: Preliminary data suggest that thyroid hormone levels show a mean increase of about 20% immediately after fine-needle aspiration. SIGNIFICANCE: The implication of this finding on patient care should be determined on an individual basis. |
| Authors | H Cengiz Alpay, Turgut Kalidag, Erol Keles, Irfan Kaygusuz, Sinasi Yalcin, Zeliha Kapusuz
(Affiliation: Firat University Medical Faculty, Otorhinolaryngology Department, Elaziğ, Turkey. hayrettincengizalpay at yahoo.com)
|
| Journal | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
(Otolaryngol Head Neck Surg)
Vol. 136
Issue 6
Pg. 942-5
(Jun 2007)
ISSN: 0194-5998 United States |
| PMID | 17547984
(Publication Type: Journal Article)
|
| Chemical References |
- Thyroid Hormones
- Triiodothyronine
- Thyroxine
- Thyrotropin
- Thyroglobulin
|
| Topics |
- Adult
- Aged
- Biopsy, Fine-Needle
- Diagnosis, Differential
- Female
- Humans
- Male
- Middle Aged
- Reference Values
- Thyroglobulin
(blood)
- Thyroid Gland
(pathology)
- Thyroid Hormones
(blood)
- Thyroid Nodule
(pathology)
- Thyrotropin
(blood)
- Thyroxine
(blood)
- Triiodothyronine
(blood)
|
