[PK/PD analysis and proper dosage of antimicrobial agents for effective and safe treatment of infectious diseases].

Abstract

The dosage of antimicrobial agents from PK/PD analysis is now considered important for using these agents effectively and safely. In this paper, I will discuss the proper dosage of antimicrobial agents from the point of PK/PD analysis. I will also discuss the correlation between the safety profile and pharmacokinetic parameters of the agents. It is my hope that all pharmacists will understand the proper use of antimicrobial agents and thus will assure the effective and safe treatment of patients with infectious diseases.

• Authors: Seiji Hori
• Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan (Yakugaku Zasshi) Vol. 127 Issue 6 Pg. 931-7 (Jun 2007) ISSN: 0031-6903 [Print] Japan
• PMID: 17541242 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Anti-Infective Agents

Topics

• Anti-Infective Agents (administration & dosage, adverse effects, pharmacokinetics)
• Communicable Diseases (drug therapy)
• Dose-Response Relationship, Drug
• Drug-Related Side Effects and Adverse Reactions
• Humans