Botulinum toxin for the treatment of spasticity in children: attainment of treatment goals.

Abstract

Forty patients (mean age 5 years) with a spastic disorder treated by botulinum injections (53 sessions) were evaluated for functional outcome in terms of achievement of their individual predetermined goals of treatment, rated on a modified Goal Attainment Scale from 1 (worsening function) to 4 (improved gross motor function). At the 2-week follow-up, 40% had a score of 1, 33% a score of 2, and 13% a score of 3; 12% showed no functional change. Botulinum treatments failed to significantly improve the gross motor function in this patient group. Treatment goals and expectations should clearly be established beforehand.

• Authors: Daniel M Weigl, Nili Arbel, Kalman Katz, Tali Becker, Elhanan Bar-On
• Journal: Journal of pediatric orthopedics. Part B (J Pediatr Orthop B) Vol. 16 Issue 4 Pg. 293-6 (Jul 2007) ISSN: 1060-152X [Print] United States
• PMID: 17527109 (Publication Type: Evaluation Study, Journal Article)

Chemical References

• Neuromuscular Agents
• Botulinum Toxins, Type A

Topics

• Adolescent
• Botulinum Toxins, Type A (therapeutic use)
• Cerebral Palsy (classification, drug therapy, physiopathology)
• Child
• Child, Preschool
• Female
• Follow-Up Studies
• Humans
• Infant
• Lower Extremity (physiopathology)
• Male
• Muscle Spasticity (drug therapy, physiopathology)
• Neuromuscular Agents (therapeutic use)
• Treatment Outcome