Bleomycin induced hyperpigmentation with yolk sac tumor.

Abstract	Hyperpigmentation is one of the cutaneous side effects of chemotherapautic agents, but it is usually accepted as a cosmetic problem. We report a child with yolk sac tumor who developed localized pigmentation after the first course of chemotherapy regimen that included cisplatin, etoposide and bleomycin. The hyperpigmentation was diffuse scattered, flagellate like and linear streaking which was thought to be mainly related to the skin toxicity of bleomycin.
Authors	Nilgun Yaris, Murat Cakir, Mukaddes Kalyoncu, Aysenur Okten
Journal	Indian journal of pediatrics (Indian J Pediatr) Vol. 74 Issue 5 Pg. 505-6 (May 2007) ISSN: 0973-7693 [Electronic] India
PMID	17526968 (Publication Type: Case Reports, Journal Article)
Chemical References	Antibiotics, Antineoplastic Bleomycin
Topics	Antibiotics, Antineoplastic (adverse effects) Bleomycin (adverse effects) Child, Preschool Endodermal Sinus Tumor (drug therapy) Female Humans Hyperpigmentation (chemically induced) Time Factors

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