[A randomized controlled trail of maprotiline treatment of depressive disorder].

Abstract

In order to evaluate the clinical effects of maprotiline (home made), the authors made a clinical comparison with Ludimil (Cida-Geigy) 96 cases (66 endogenous depression and 30 neurotic depression) meet the CMA diagnostic criteria (1984) were analysed. The patients' symptoms were assessed with HAMD, side effects with TESS. The study group included 72 patients treated with chinese product, the rest cases as control group treated with Ludimil. No significant differences of efficacy in terms of age, sex and duration of symptoms were found in both groups. After the six-week course of Maprotiline treatment, the authors found the dosage, therapeutic effect and adverse reaction in both groups are very similar. It is concluded that the chinese product is safe and effective.

• Authors: M Lei
• Journal: Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry (Zhonghua Shen Jing Jing Shen Ke Za Zhi) Vol. 24 Issue 5 Pg. 265-7, 316 (Oct 1991) ISSN: 0412-4057 [Print] China
• PMID: 1752175 (Publication Type: Clinical Trial, English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Maprotiline

Topics

• Depressive Disorder (drug therapy)
• Female
• Humans
• Male
• Maprotiline (therapeutic use)