[Effects of the long-term tamponade with Densiron on the lens].

Abstract

BACKGROUND:

This study aims to analyse the long-term effect of Densiron on the crystalline lens.

MATERIALS AND METHODS:

Eleven patients (53-77 years old) underwent macular surgery with pars plana vitrectomy and intraocular tamponade with Densiron. After 2-4 months the Densiron was removed. The lens was extracted by phacoemulsification and an intraocular lens was implanted. Visual acuity, slit-lamp examination and fundus ophthalmoscopy were performed pre- and postoperatively. During surgery the anterior chamber, the lens und the posterior capsule of the lens were photographed and analysed.

RESULTS:

All patients (mean age: 68 +/- 7 years) developed a nuclear cataract combined with a posterior capsule opacification. Four patients demonstrated vacuoles within the lens cortex and in five patients a pseudohypopyon consisting of emulsified Densiron was found. Mean visual acuity was 0.1 before removal of Densiron and 0.1 postoperatively.

CONCLUSIONS:

Long-term tamponade with Densiron was complicated by early cataract formation in patients aged 68 years on average. The additional posterior capsule opacification showed a distinct pattern and localisation when compared to the use of 5000 mPas-silicone oil as tamponade.

• Authors: A Lappas, B Kirchhof, W Konen
• Journal: Klinische Monatsblatter fur Augenheilkunde (Klin Monbl Augenheilkd) Vol. 224 Issue 5 Pg. 434-7 (May 2007) ISSN: 0023-2165 [Print] Germany
• Vernacular Title: Linsenveränderungen nach Langzeittamponade mit schwerem Ol (Densiron).
• PMID: 17516376 (Publication Type: Clinical Trial, English Abstract, Journal Article)

Chemical References

• Silicone Oils
• densiron

Topics

• Aged
• Cataract (chemically induced, diagnosis)
• Female
• Glaucoma (chemically induced, diagnosis)
• Humans
• Lens, Crystalline (drug effects)
• Male
• Middle Aged
• Silicone Oils (adverse effects)
• Treatment Outcome