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Paradoxical embolus illustrating speed of action of recombinant tissue plasminogen activator in massive pulmonary embolism.

Abstract
A case of a patient who presented with massive pulmonary embolism (PE) requiring thrombolysis with alteplase is reported. The subsequent presence of a patent foramen ovale and paradoxical embolism clinically demonstrated the speed of action of the recombinant tissue plasminogen activator. The advantage of this class of medication when considering the treatment options for a PE in an acute setting is highlighted.
AuthorsH Madani, P A Ransom
JournalEmergency medicine journal : EMJ (Emerg Med J) Vol. 24 Issue 6 Pg. 441 (Jun 2007) ISSN: 1472-0213 [Electronic] England
PMID17513552 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Fibrinolytic Agents
  • Tissue Plasminogen Activator
Topics
  • Adult
  • Dose-Response Relationship, Drug
  • Embolism, Paradoxical (complications, drug therapy)
  • Female
  • Femoral Artery
  • Fibrinolytic Agents (therapeutic use)
  • Humans
  • Pulmonary Embolism (complications, drug therapy)
  • Thrombolytic Therapy (methods)
  • Tissue Plasminogen Activator (therapeutic use)
  • Treatment Outcome

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