Puerperal
pyrexia and
sepsis are among the leading causes of preventable maternal morbidity and mortality not only in developing countries but in developed countries as well. Most postpartum
infections take place after hospital discharge, which is usually 24 hours after delivery. In the absence of postnatal follow-up, as is the case in many developing countries, many cases of
puerperal infections can go undiagnosed and unreported. Besides
endometritis (
endomyometritis or endomyoparametritis),
wound infection,
mastitis,
urinary tract infection, and septic
thrombophlebitis are the chief causes of
puerperal infections. The predisposing factors leading to the development of
sepsis include home birth in unhygienic conditions, low socioeconomic status, poor nutrition, primiparity,
anemia, prolonged
rupture of membranes, prolonged labor, multiple vaginal examinations in labor,
cesarean section, obstetrical maneuvers, retained secundines within the uterus and
postpartum hemorrhage. Maternal complications include
septicemia, endotoxic
shock,
peritonitis or
abscess formation leading to surgery and compromised future fertility. The transmissions of infecting organisms are typically categorized into nosocomial, exogenous, and endogenous.
Nosocomial infections are acquired in hospitals or other health facilities and may come from the hospital environment or from the patient's own flora. Exogenous
infections come from external contamination, especially when deliveries take place under unhygienic conditions. Endogenous organisms, consisting of mixed flora colonizing the woman's own genital tract, are also a source of
infection in puerperal
sepsis. Aseptic precautions, advances in investigative tools and the use of
antibiotics have played a major role in reducing the incidence of
puerperal infections. Part II of this review describes the best management of
wound infection, pelvic
abscess,
episiotomy infection,
thrombophlebitis,
mastitis,
urinary tract infection, and miscellaneous
infections.
TARGET AUDIENCE: Obstetricians & Gynecologists, Family Physicians Learning Objectives: After completion of this article, the reader should be able to recall that world wide puerperal
sepsis is a leading cause of maternal mortality, state that many of the predisposing factors are preventable, explain that both
nosocomial infections as well as exogenous
infections are serious factors, and relate that septic techniques and
antibiotics can play a major role in reducing the incidence of
puerperal infections.