Hypoxia up-regulates the angiogenic cytokine secretoneurin via an HIF-1alpha- and basic FGF-dependent pathway in muscle cells.
Abstract |
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Authors | Margot Egger, Wilfried Schgoer, Arno G E Beer, Johannes Jeschke, Johannes Leierer, Markus Theurl, Silke Frauscher, Oren M Tepper, Andreas Niederwanger, Andreas Ritsch, Marianne Kearney, Julia Wanschitz, Geoffrey C Gurtner, Reiner Fischer-Colbrie, Guenter Weiss, Hildegunde Piza-Katzer, Douglas W Losordo, Josef R Patsch, Peter Schratzberger, Rudolf Kirchmair |
Journal | FASEB journal : official publication of the Federation of American Societies for Experimental Biology
(FASEB J)
Vol. 21
Issue 11
Pg. 2906-17
(Sep 2007)
ISSN: 1530-6860 [Electronic] United States |
PMID | 17504977
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- DNA Primers
- Hif1a protein, mouse
- Hypoxia-Inducible Factor 1, alpha Subunit
- Neuropeptides
- RNA, Small Interfering
- Secretogranin II
- VEGFA protein, human
- Vascular Endothelial Growth Factor A
- NAD
- Fibroblast Growth Factor 2
- secretoneurin
- Pcsk6 protein, mouse
- Proprotein Convertases
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Topics |
- Animals
- Blotting, Western
- Cell Hypoxia
- Cells, Cultured
- DNA Primers
(chemistry)
- Endothelium, Vascular
(cytology, metabolism)
- Extremities
(surgery)
- Fibroblast Growth Factor 2
(metabolism)
- Fluorescent Antibody Technique
- Hypoxia-Inducible Factor 1, alpha Subunit
(metabolism)
- Ischemia
(metabolism, pathology)
- Mice
- Mice, Inbred C57BL
- Muscle, Smooth, Vascular
(blood supply, cytology, metabolism)
- Myoblasts
(metabolism)
- NAD
(metabolism)
- Neovascularization, Physiologic
- Neuropeptides
(metabolism)
- Pituitary Neoplasms
(blood supply, metabolism, pathology)
- Polymerase Chain Reaction
- Proprotein Convertases
(metabolism)
- RNA, Small Interfering
(pharmacology)
- Radioimmunoassay
- Rats
- Secretogranin II
(metabolism)
- Signal Transduction
- Skin
(metabolism)
- Transfection
- Vascular Endothelial Growth Factor A
(metabolism)
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