HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Varicella-zoster infection with encephalopathy, pneumonia, and renal failure: a case report.

Abstract
Primary varicella-zoster (VZ) infection is rare in adults, but the rate of morbidity and mortality is higher than in children. Pneumonia is the most common complication of primary VZ infection in adults. Moreover, varicella pneumonia associated with acute renal failure and acute encephalopathy is very rare. This study reports on a case of disseminated VZ infection successfully treated with acyclovir. The patient was otherwise healthy and denied previous systemic or infectious disease. The initial diagnosis was varicella pneumonia. However, multiple organ involvement subsequently was found in several organs, including the kidney, brain, lung, liver, blood, and skin. The reactivation of VZ infection was strongly suspected. Abnormal renal and liver function and thrombocytopenia also were noted. The patient with chickenpox was treated successfully with acyclovir without complication. In conclusion, multiple organ involvement is a rare complication of VZ infection in adults. In the severe case presented here, adequate intravenous acyclovir administration and close observation of the general condition were essential for successfully treating disseminated VZ infection without complications.
AuthorsFeng-Rong Chuang, Chih-Hsiung Lee, Chung-Hua Chuang, Wen-Chin Lee, Chih-Chao Yang, Te-Chuan Chen, Cheng-Hsien Lu, Hung-Yu Chang, Ming-Jen Sheu, I-Kuan Wang
JournalRenal failure (Ren Fail) Vol. 29 Issue 3 Pg. 359-62 ( 2007) ISSN: 0886-022X [Print] United States
PMID17497452 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antiviral Agents
  • Acyclovir
Topics
  • Acute Kidney Injury (drug therapy, virology)
  • Acyclovir (therapeutic use)
  • Adult
  • Antiviral Agents (therapeutic use)
  • Chickenpox (complications, drug therapy)
  • Encephalitis, Varicella Zoster (drug therapy, virology)
  • Herpesvirus 3, Human
  • Humans
  • Male
  • Pneumonia, Viral (drug therapy, virology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password: