Abstract | OBJECTIVES: We evaluated the results of surgical treatment and postoperative radiotherapy and prognostic factors in patients with primary tongue carcinoma. PATIENTS AND METHODS: The study included 60 patients (31 males, 29 females; median age 54 years; range 22 to 82 years) who underwent surgery and postoperative radiotherapy for oral tongue cancer. Tumor staging based on the AJCC-1997 criteria was as follows: stage I (n=1), stage II (n=21), stage III (n=12), and stage IVA (n=26). Surgery included hemiglossectomy (n=46, 76%), partial (n=13, 22%) and total (n=1, 2%) glossectomy. Neck dissection was performed in 47 patients (78%). Radiotherapy dose was generally 6000 cGy/30 fr. The median follow-up was 51 months (range 5 to 180 months). RESULTS: The five-year overall and relapse-free survival rates were 50% and 47%, respectively. Survival at five years was 70% for stage I-III, and 20% for stage IVA. Most of the relapses occurred in the first two years after treatment. Recurrences were encountered in 31 patients (52%). The median survival after recurrence was eight months (range 1 to 53 months). In multivariate analyses, significant prognostic factors for overall survival and locoregional control were tumor size, stage, N stage, extracapsular lymph node spread, and total duration of radiotherapy. Complications were within acceptable limits. CONCLUSION:
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Authors | Ahmet Karadeniz, Mert Saynak, Züleyha Kadehci, Merdan Fayda, Görkem Aksu, Hümeyra Kocaelli, Günter Hafiz |
Journal | Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
(Kulak Burun Bogaz Ihtis Derg)
Vol. 17
Issue 1
Pg. 1-6
( 2007)
ISSN: 1300-7475 [Print] Turkey |
Vernacular Title | Dil kanserinde kombine tedavi (cerrahi ve radyoterapi) sonuçlari ve prognostik faktörler. |
PMID | 17483603
(Publication Type: Evaluation Study, Journal Article)
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Carcinoma, Squamous Cell
(mortality, pathology, radiotherapy, surgery)
- Combined Modality Therapy
- Disease-Free Survival
- Female
- Humans
- Male
- Middle Aged
- Neoplasm Recurrence, Local
(mortality, pathology, radiotherapy, surgery)
- Neoplasm Staging
- Survival Analysis
- Tongue Neoplasms
(mortality, pathology, radiotherapy, surgery)
- Treatment Outcome
- Turkey
(epidemiology)
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