Abstract | AIM: To determine the prevalence and risk factors associated with secondary glaucoma postcongenital cataract surgery. METHODS: RESULTS: The statistical methods were the use of Kaplan-Meier survival analysis and Multivariate Cox hazards regression analysis. The mean follow-up was 6.3 (SD 5.0) years (median 4.6 years; range 0.5 to 20.3 years). Glaucoma developed in 36 of 234 patients (15.4%). Multivariate Cox proportional hazards regression analysis identified age less than 9 months at time of surgery (RR 2.9, 95% CI 1.3 to 7.7; p = 0.03), microcornea (RR 3.7, 95% CI 2.0 to 7.0; p<0.001), and follow-up time as important predictors of glaucoma. PHPV (RR 1.4, 95% CI 0.7 to 2.7; p = 0.41) and primary posterior capsulotomy/anterior vitrectomy (RR 2.2, 95% CI 0.9 to 5.5; p = 0.17) were not significantly associated with secondary glaucoma in the multivariate model. The mean time to glaucoma after congenital cataract surgery was 4.9 years (range 2 weeks to 16.8 years). CONCLUSION: Secondary glaucoma is an important sequela in patients who undergo surgery for congenital cataracts. It is imperative that these patients get lifelong surveillance, as glaucoma can occur years after the initial operation.
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Authors | B N Swamy, F Billson, F Martin, C Donaldson, S Hing, R Jamieson, J Grigg, J E H Smith |
Journal | The British journal of ophthalmology
(Br J Ophthalmol)
Vol. 91
Issue 12
Pg. 1627-30
(Dec 2007)
ISSN: 1468-2079 [Electronic] England |
PMID | 17475699
(Publication Type: Journal Article)
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Topics |
- Adolescent
- Adult
- Age Factors
- Cataract
(congenital)
- Cataract Extraction
(adverse effects)
- Child
- Child, Preschool
- Cornea
(abnormalities)
- Female
- Follow-Up Studies
- Glaucoma
(epidemiology, etiology)
- Humans
- Infant
- Kaplan-Meier Estimate
- Lens Implantation, Intraocular
- Male
- Predictive Value of Tests
- Prevalence
- Proportional Hazards Models
- Regression Analysis
- Retrospective Studies
- Risk Factors
- Time Factors
- Vitreous Body
(abnormalities)
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