Abstract | OBJECTIVE: METHODS: RESULTS: In all 41 cases, complete resections were performed, with no operative mortality. The histologically complete response rate, major response rate, and minor response rate were 17.1% (7/41), 56.1% (23/41), and 26.8% (11/41), respectively. The 5-year overall survival was 52.7%. There were no differences in survival between taxane groups. Both the complete response and the major response groups revealed a significantly better 5-year survivals than the minor response group (85.7%, P = .044, 52.4%, P = .01). Even with persistent N2 disease, the 5-year survival in the major response group (66%) was promising. With the combination of conventional computed tomography and positron-emission tomography with fludeoxyglucose F 18 for reevaluation, eligible patients could be selected for this protocol. CONCLUSION:
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Authors | Hiroyasu Yokomise, Masashi Gotoh, Taku Okamoto, Yasumichi Yamamoto, Shinya Ishikawa, Takashi Nakashima, Daiki Masuya, Dage Liu, Cheng-long Huang |
Journal | The Journal of thoracic and cardiovascular surgery
(J Thorac Cardiovasc Surg)
Vol. 133
Issue 5
Pg. 1179-85
(May 2007)
ISSN: 1097-685X [Electronic] United States |
PMID | 17467426
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
- Bridged-Ring Compounds
- Taxoids
- taxane
- Carboplatin
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Topics |
- Adult
- Aged
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Bridged-Ring Compounds
(administration & dosage)
- Carboplatin
(administration & dosage)
- Carcinoma, Non-Small-Cell Lung
(mortality, pathology, surgery, therapy)
- Female
- Humans
- Lung Neoplasms
(mortality, pathology, surgery, therapy)
- Male
- Middle Aged
- Neoadjuvant Therapy
- Radiotherapy Dosage
- Survival Rate
- Taxoids
(administration & dosage)
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