Recent immunologic considerations regarding the itch and treatment of scabies.

Abstract

Scabies continues to be a major public health problem. Recent findings reveal that these mites produce substances that modulate the host's immune response resulting in the latency period prior to symptoms. In terms of treatment, two cases of ivermectin resistance have come to fore in Australia in patients treated over fifty times with the agent. Additionally, work in the development of vaccination of hosts with antigenic midgut proteins of mites to control ectoparasitic infestations continues.

• Authors: Craig G Burkhart
• Journal: Dermatology online journal (Dermatol Online J) Vol. 12 Issue 7 Pg. 7 (Dec 10 2006) ISSN: 1087-2108 [Electronic] United States
• PMID: 17459293 (Publication Type: Journal Article)

Chemical References

• Antiparasitic Agents
• Vaccines
• Ivermectin

Topics

• Animals
• Antiparasitic Agents (therapeutic use)
• Drug Resistance
• Humans
• Ivermectin (therapeutic use)
• Pruritus (immunology)
• Sarcoptes scabiei (immunology)
• Scabies (complications, drug therapy, immunology, prevention & control)
• Vaccines