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Retinal detachment in patients with acute retinal necrosis: a case series.

AbstractBACKGROUND:
Acute retinal necrosis is a rare and severe infectious ocular disease frequently complicated by retinal detachment.
PATIENTS AND METHODS:
Records of six consecutive eyes from five patients with acute retinal necrosis were reviewed.
RESULTS:
PCR analysis of intraocular fluids was positive for Varizella zoster virus, Herpes virus 1 or 2. Treatment consisted of systemic acyclovir, systemic and local corticosteroids as well as aspirin. Progression of the necrosis could be effectively controlled, however all eyes developed retinal detachment within 55 +/- 24 days. Retinal surgery including pars plana vitrectomy, encircling scleral buckling, liquid silicone or gas filling led to retinal reattachment in all patients during the follow-up time (590 +/- 242 days). The mean visual acuity at the end of the follow-up time was 0.4 +/- 0.3.
CONCLUSIONS:
The diagnosis of acute retinal necrosis is reliably confirmed using PCR analysis of intraocular fluids. Currently available treatments are effective in stopping progression of the necrosis. There is, however, a high risk of retinal detachment, which can be successfully treated with vitreoretinal surgery.
AuthorsM Abegg, M Kurz-Levin, H Helbig
JournalKlinische Monatsblatter fur Augenheilkunde (Klin Monbl Augenheilkd) Vol. 224 Issue 4 Pg. 360-3 (Apr 2007) ISSN: 0023-2165 [Print] Germany
PMID17458815 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antiviral Agents
Topics
  • Adolescent
  • Adult
  • Aged
  • Antiviral Agents (therapeutic use)
  • Combined Modality Therapy
  • Eye Infections, Viral (complications, diagnosis, therapy)
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retinal Detachment (diagnosis, etiology, therapy)
  • Retinal Necrosis Syndrome, Acute (complications, diagnosis, therapy)
  • Vitrectomy

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