[Hypocomplementemic urticarial vasculitis syndrome. Successful therapy with intravenous immunoglobulins].

Abstract

Autoimmune diseases can initially present as chronic urticaria. We describe the course of a patient with hypocomplementemic urticarial vasculitis syndrome (HUVS) as well as his successful treatment with high-dose intravenous immunoglobulins (IVIG). HUVS was diagnosed clinically and confirmed by histology and laboratory studies. After only one cycle with IVIG (2 g/kg) all HUVS symptoms were significantly decreased.

• Authors: P Staubach-Renz, E von Stebut, W Bräuninger, M Maurer, K Steinbrink
• Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete (Hautarzt) Vol. 58 Issue 8 Pg. 693-7 (Aug 2007) ISSN: 0017-8470 [Print] Germany
• Vernacular Title: Hypokomplementämisches Urtikaria-Vaskulitis-Syndrom. Erfolgreiche Therapie mit intravenösen Immunglobulinen.
• PMID: 17453168 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Complement C3
• Complement C4
• Immunoglobulins, Intravenous
• Complement C1q

Topics

• Adult
• Angioedema (diagnosis, drug therapy, immunology, pathology)
• Autoimmune Diseases (diagnosis, drug therapy, immunology, pathology)
• Biopsy
• Complement C1q (deficiency)
• Complement C3 (deficiency)
• Complement C4 (deficiency)
• Diagnosis, Differential
• Follow-Up Studies
• Humans
• Immunoglobulins, Intravenous (administration & dosage)
• Infusions, Intravenous
• Lupus Erythematosus, Systemic (diagnosis, drug therapy, immunology, pathology)
• Male
• Skin (pathology)
• Vasculitis, Leukocytoclastic, Cutaneous (diagnosis, drug therapy, immunology, pathology)