A novel cytotoxic lignan from Seseli annuum L.

Abstract	A new tetrahydrofuranoid lignan named seselinone was isolated from the aerial parts of Seseli annuum, together with three known lignans (eudesmin, magnone A and hernone) and prenylated coumarin umbelliprenin. Seselinone and eudesmin showed cytotoxic activity against C6 rat glioma cell cultures.
Authors	Ivan Vucković, Vladimir Trajković, Slobodan Macura, Vele Tesević, Peda Janaćković, Slobodan Milosavljević
Journal	Phytotherapy research : PTR (Phytother Res) Vol. 21 Issue 8 Pg. 790-2 (Aug 2007) ISSN: 0951-418X [Print] England
PMID	17450503 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Copyright	(c) 2007 John Wiley & Sons, Ltd.
Chemical References	Antineoplastic Agents, Phytogenic Lignans seselinone
Topics	Animals Antineoplastic Agents, Phytogenic (chemistry, toxicity) Apiaceae (chemistry) Cell Line, Tumor Glioma (pathology) Lignans (chemistry, toxicity) Plant Components, Aerial (chemistry) Rats

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