| Abstract | OBJECTS: To show the clinical results of a corpus callosotomy (CC) treatment using conformal stereotactic radiosurgery (SRS) on a patient with medically intractable multifocal epilepsy. MATERIALS AND METHODS: A 17-year-old male patient underwent corpus callosotomy conformal SRS using a dedicated linear accelerator (linac) with dynamic arcs technique. The prescribed dose was 36.0 Gy at the periphery of the rostrum, genu, and a half of the body of the corpus callosum (CCA). At 8 months after conformal SRS, the patient developed a significant brain edema and moderate transitory motor deficit, which were controlled with steroids. After 32 months follow-up, there is an improvement of 84% on drop attacks and generalized tonic-clonic seizures. CONCLUSIONS: Conformal SRS for corpus callosotomy with a single isocenter reproduce the results reported on literature using Gamma Knife-based SRS. The results show that this technique is safe and demonstrate its efficacy to control seizures. |
| Authors | M A Celis, S Moreno-Jiménez, J M Lárraga-Gutiérrez, M A Alonso-Vanegas, O A García-Garduño, I E Martínez-Juárez, M C Fernández-Gónzalez
(Affiliation: Unidad de Radioneurocirugía, Instituto Nacional de Neurología y Neurocirugía, Insurgentes sur 3877, La Fama, Tlalpan, 14269, México, D.F., México. macelisl at yahoo.com.mx)
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| Journal | Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
(Childs Nerv Syst)
Vol. 23
Issue 8
Pg. 917-20
(Aug 2007)
ISSN: 0256-7040 Germany |
| PMID | 17450365
(Publication Type: Case Reports, Journal Article)
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| Chemical References |
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| Topics |
- Adolescent
- Anticonvulsants
(therapeutic use)
- Brain Edema
(etiology, pathology, therapy)
- Corpus Callosum
(pathology, surgery)
- Drug Resistance
- Electroencephalography
- Epilepsy
(surgery)
- Humans
- Magnetic Resonance Imaging
- Male
- Paresis
(etiology)
- Particle Accelerators
- Postoperative Complications
(pathology, therapy)
- Radiosurgery
- Radiotherapy, Conformal
- Tomography, X-Ray Computed
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