Abstract | BACKGROUND: METHODS: The primary end point was the magnitude of ST-segment resolution (STR) (> 70%) measured immediately, 90 minutes and 6 hours after PCI, myocardial blush grade and slow flow or no-reflow. Secondary end points were left ventricular end-diastolic volume (LVEDV), left ventricle ejection fraction (LVEF) and major adverse cardiac events (MACEs) including death, myocardial infarction, target vessel revascularization and stroke at 30 days. RESULTS: A total of 122 patients were equally divided into Diver CE group and Guardwire Plus group, which were comparable by age ((60 +/- 14) years vs (60 +/- 13) years), male (82% vs 84%), diabetes (31% vs 28%), previous coronary artery disease (25% vs 23%), onset-to-angiogram ((350 +/- 185) min vs (345 +/- 180) min), and use of glycoprotein IIb/IIIa inhibitor (11% vs 13%). The magnitude of ST-segment resolution was similar in the two groups as ST-segment resolution > 70% (57% vs 59%; P > 0.05). Similar slow flow/no-reflow rates were observed in the Diver CE group (8%) and the Guardwire Plus group (7%). TIMI flow grade 3 was obtained in 95% vs 97% patients, respectively (P > 0.05). Myocardial blush grade 3 was similar (70% vs 72%; P > 0.05). Thirty-day clinical outcome was comparable (LVEF, 0.54 +/- 0.12 vs 0.53 +/- 0.11; death, 3% vs 3%; myocardial infarction, 2% vs 0%; and target vessel revascularization, 2% vs 2%; P > 0.05, respectively). CONCLUSIONS: Removal of thrombus burden with the Diver CE catheter before stenting leads to similar improvement of myocardial reperfusion in patients with inferior STEMI and total occlusion of the proximal right coronary artery (= 3 mm in diameter) compared with the Guardwire Plus device, as illustrated by a reduced risk of distal embolization and improved ST-segment resolution.
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Authors | Hong-bing Yan, Jian Wang, Nan Li, Xiao-ling Zhu, Hai Gao, Hui Ai, Xiang Li, Ming Ye, Yun-peng Chi, Hong Zhang |
Journal | Chinese medical journal
(Chin Med J (Engl))
Vol. 120
Issue 7
Pg. 557-61
(Apr 05 2007)
ISSN: 0366-6999 [Print] China |
PMID | 17442202
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
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Topics |
- Adult
- Aged
- Angioplasty, Balloon, Coronary
(methods)
- Coronary Angiography
- Coronary Circulation
- Female
- Humans
- Male
- Middle Aged
- Myocardial Infarction
(diagnostic imaging, physiopathology, therapy)
- Suction
- Thrombectomy
(instrumentation)
- Ventricular Function, Left
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