| Abstract | PURPOSE: To report on the clinical features of three cases of polypoidal choroidal vasculopathy (PCV) during long-term follow-up after photodynamic therapy (PDT). DESIGN: Interventional case reports. METHODS: Among the participants in the Japanese Age-Related Macular Degeneration Trial (JAT) at our hospital, a PCV was seen in three eyes at baseline on retrospective analysis of indocyanine green angiography (ICGA) using fundus camera. We report the clinical features of these cases during more than 4 years follow-up. RESULTS: The mean number of PDT treatments was 5.7. Improved visual acuity (VA) and cessation of fluorescein leakage was achieved within 18 months in all eyes; however, subretinal hemorrhage and subfoveal fluid recurred due to new or recurrent PCV. The final VA decreased markedly in two eyes. CONCLUSIONS: The eyes with PCV, which had been treated successfully with PDT, may have developed new or recurrent PCV during long-term follow-up. Periodical ICGA would be needed to detect abnormal choroidal vascular changes. |
| Authors | Kaori Sayanagi, Fumi Gomi, Miki Sawa, Masahito Ohji, Yasuo Tano
(Affiliation: Department of Ophthalmology, Osaka University Medical School, Room E7, 2-2 Yamadaoka, 565-0871 Suita, Japan.)
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| Journal | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie
(Graefes Arch Clin Exp Ophthalmol)
Vol. 245
Issue 10
Pg. 1569-71
(Oct 2007)
ISSN: 0721-832X Germany |
| PMID | 17437122
(Publication Type: Case Reports, Journal Article)
|
| Chemical References |
- Coloring Agents
- Photosensitizing Agents
- Porphyrins
- verteporfin
- Indocyanine Green
|
| Topics |
- Aged
- Choroid
(blood supply)
- Coloring Agents
(diagnostic use)
- Female
- Fluorescein Angiography
- Follow-Up Studies
- Humans
- Indocyanine Green
(diagnostic use)
- Male
- Peripheral Vascular Diseases
(diagnosis, drug therapy)
- Photochemotherapy
- Photosensitizing Agents
(therapeutic use)
- Porphyrins
(therapeutic use)
- Retrospective Studies
- Visual Acuity
|
