[Clinical observation on effect of compound Shiwei Tablet in treating urinary tract infection].

To evaluate the safety and efficacy of Compound Shiwei Tablet (CST) in treating upper and lower urinary tract infection (UTI, pyretic stranguria of dampness-heat of the Lower-jiao type in 'TCM).
A multi-center, randomized, and opened clinical trial was conducted in the UTI patients with Sanjin Tablet (ST) as the parallel positive control medicine. The comprehensive efficacy, effect on TCM syndrome score, and change of urinary leukocyte count were observed, and the adverse reaction was recorded.
In the 147 upper UTI cases and the 312 lower UTI cases after treatment, the comprehensive effect was higher and urinary leukocyte was less in the CST treated patients than in the ST treated patients (P < 0.05); but significant difference in the improvement of TCM symptoms was found between them only in the lower UTI cases ( P < 0.05); and no adverse reaction was observed during the treatment course.
CST has definite therapeutic efficacy on UTI and is safe in clinical application.
AuthorsYong-li Zhan, Xiu-ying Li, Sheng-xian Wu
JournalZhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine / Zhongguo Zhong xi yi jie he xue hui, Zhongguo Zhong yi yan jiu yuan zhu ban (Zhongguo Zhong Xi Yi Jie He Za Zhi) Vol. 27 Issue 3 Pg. 249-51 (Mar 2007) ISSN: 1003-5370 [Print] China
PMID17432690 (Publication Type: English Abstract, Journal Article, Multicenter Study, Randomized Controlled Trial)
Chemical References
  • Drugs, Chinese Herbal
  • Tablets
  • shiwei
  • Uric Acid
  • Adult
  • Drugs, Chinese Herbal (therapeutic use)
  • Female
  • Humans
  • Male
  • Medicine, Chinese Traditional
  • Middle Aged
  • Phytotherapy
  • Syndrome
  • Tablets
  • Treatment Outcome
  • Uric Acid (urine)
  • Urinary Tract Infections (diagnosis, drug therapy, urine)

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